• Percentage contribution to free glutamate intake

  2021-10-23

  

  Percentage contribution to free glutamate intake was also calculated at the food item level. A list of the top 30 foods for children and adults are presented separately in Table 2. The top 4 foods included in this list are watermelon, raw; tomato catsup; tomatoes, raw; and roll, white, soft. These a

• FFAR is highly expressed not only in cells but also

  2021-10-23

  

  FFAR1 is highly expressed not only in β cells but also in α rxr receptor (Segerstolpe et al., 2016), which gives the interesting perspective that 20-HETE may function both as an autocrine and as a paracrine regulator of islet cell function (Figure 1A), i.e., acting in symphony with the many other in

• Caffeine decreased EAAT and EAAT expression levels

  2021-10-23

  

  Caffeine decreased EAAT1 and EAAT2 (R,S)-Anatabine synthesis levels in P2 fraction, as well as [3H]d-aspartate uptake; however, as soon as caffeine is removed from incubation, [3H]-d-Aspartate uptake is recovered to control levels, eliminating the possibility of caffeine as a cell death inducer. I

• The EEGs of these six

  2021-10-23

  

  The EEGs of these six patients interestingly showed focal, multi-focal and generalized spikes, which was an exclusion criteria in our study as we selected our cohort to exclusively represent focal epilepsy. Remarkably all of these cases were diagnosed with paroxysmal exercise-induced dyskinesia (PED

• GK also called hexokinase IV or D is

  2021-10-23

  

  GK, also called hexokinase IV or D, is a glycolytic enzyme that converts hexokinase inhibition to glucose-6-phosphate. GK has unique characteristics compared with those of the ubiquitously expressed hexokinase isoforms I–III, and is predominantly expressed in the pancreas and liver. In pancreatic β-

• br Clinical development of FGFR inhibitors in

  2021-10-22

  

  Clinical development of FGFR inhibitors in breast cancer The rationale to explore the role of FGFR inhibitors in patients with breast cancer comes from a variety of sources. These include genomic aberrations frequently identified in the FGF/FGFR pathway in breast cancer, the increased sensitivity

• br Introduction The brain contains abundant fatty acids

  2021-10-22

  

  Introduction The brain contains abundant fatty acids, which serve as constituents of membranes and as an energy source. In addition, fatty acids and their metabolites contribute to signal transduction between neurons or neurons and glial cells, suggesting that fatty acids play a crucial role in d

• Consistent with our gene profiling analyses

  2021-10-22

  

  Consistent with our gene-profiling analyses showing that genes involved in mutual compensation of EGFR or integrin/FAK were significantly downregulated by Tinagl1 overexpression, treatment with r-Tinagl1 inhibited the activation of EGFR and FAK in vitro, and phenocopied the combined inhibition of in

• br Materials and methods br Results br Discussion

  2021-10-22

  

  Materials and methods Results Discussion Directly modulating specific target proteins and signaling pathways with small-molecule drugs or agonistic Deferoxamine mesylate is widely used for cancer metastasis therapies [[39], [40], [41]]. ANXA7 acts as a metastasis suppressor in prostate can

• GSTP catalyzed reduction of Prdx enhances its

  2021-10-22

  

  GSTP1-1 catalyzed reduction of Prdx6 enhances its peroxidase activity. Using standard NADPH/GR/GSH-coupled assays we used cell lysates from the transiently transfected resazurin australia to measure the influence of GSTP1 allelic variation on peroxidase activity. Specificity for detection of Prdx6

• Finally our work showed that HAART resulted in significant

  2021-10-22

  

  Finally, our work showed that HAART resulted in significant inter-individual variability among DEGs, which reflected the Emodepside in HIV-affected human gene expressions (Fig. 1, Fig. 2, Fig. 3, Fig. 4). These observations also highlighted the importance of determining common as well as personal sp

• In women with stage I II

  2021-10-22

  

  In women with stage I–II endometriosis [17], no difference in the implantation rate per embryo or in the clinical pregnancy rate per transfer was noted between GnRH-agonist and GnRH-antagonist protocol (18.2% vs. 15.4%, P=0.9 and 31.2% vs. 30%, P=1, respectively). It has been suggested that either

• It is increasingly argued that the immunosuppressive effects

  2021-10-22

  

  It is increasingly argued that the immunosuppressive effects of GCs are conferred indirectly by GR through the activation of genes encoding proteins that inhibit Ipratropium Bromide of proinflammatory genes 86, 87, 88. Genomic studies offer another mechanism compatible with the idea that GC-mediated

• These various observations indicate that GIP plays an

  2021-10-22

  

  These various observations indicate that GIP plays an important role in the normal compensatory islet response to high fat feeding. This likely reflects the loss of the combined actions of intra-islet GIP together with intestinally-derived GIP entering the islet vasculature following secretion from

• br Activators Many compounds are known to

  2021-10-22

  

  Activators Many compounds are known to influence the activity of Ca2+-activated K+ channels, and since hIK1 was cloned more insight has been gained on compounds that have the capacity to increase channel activity. Activation by divalent metal cations has been investigated, with Ca2+, Pb2+, Cd2+,

16069 records 584/1072 page Previous Next First page 上5页 581582583584585 下5页 Last page