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In the present study we aimed to
2021-09-22

In the present study, we aimed to investigate the effect of a common dairy and beef genetic background on the mRNA AMG-900 of the AdipoQ system and GPR109A in different adipose depots and liver. Materials and Methods Results Comparing fat masses between families (fat-type vs. lean-type cows)
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In addition to vertebrate species GnRH has been identified i
2021-09-22

In addition to vertebrate species, GnRH has been identified in invertebrates, such as in the Protochordate Ciona intestinalis (Powell et al., 1996; Adams et al., 2003), the decapods mollusk Octopus vulgaris (Iwakoshi et al., 2002), the gastropod mollusk, the sea hare Aplysia californica (Zhang et al
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Apple juice is the most consumed apple derivative since
2021-09-22

Apple juice is the most consumed apple derivative since more than 20% of freshly harvested apples are consumed as juice (Schulze et al., 2014). Apple juice production implies several technological interventions, among which are skin and pomace removal, enzymatic depectinization, and pasteurization.
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br Conclusion br Ethics statements
2021-09-22

Conclusion Ethics statements file Conflict of interest Acknowledgements This study was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MSIP) (Nos. 2011-0030074 and 2018R1D1A3B07050361) and Sookmyung Women’s University Specialization Pro
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Ghrelin contains an n octanoylation at its Ser
2021-09-22

Ghrelin contains an n-octanoylation at its Ser3 residue (Kojima et al., 1999). While des-acyl ghrelin is found in high concentrations in the blood, only the lipidated form is active at GHSR (Bednarek et al., 2000). We previously showed that ghrelin interacts with the membrane via its lipid modificat
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PU-WS13 br Conflict of interest statement br Introduction br
2021-09-18

Conflict of interest statement Introduction Gap junction assembly Induced disassembly of gap junctions The regulation of connexin and gap junction turnover are still not well understood. This is, in part, due to the fact that while the overall turnover of connexin molecules is fairly con
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In a follow up study the same research
2021-09-18

In a follow up study, the same research group further characterized FFA4 involvement in DU145 and PC-3 cancer cell lines by demonstrating that the anti-proliferative and anti-migration activities of FFA4 require the presence of LPA1 receptor (LPA1R), suggesting a mechanism consistent with negative c
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Introduction Thrombotic disorders including ischemic heart d
2021-09-18

Introduction Thrombotic disorders including ischemic heart disease, deep venous thrombosis, and ischemic stroke represent one of the most common causes of death in the world [1]. All these conditions relate to states accompanied by a shift of hemostasis balance into a coagulation side because of va
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Although drug monitoring is not usually requested there are
2021-09-18

Although drug monitoring is not usually requested, there are some cases where measurement of DOACs in calculate the concentration is useful, and of special help for managing patients at risk. These cases include the control of adherence to a therapeutic protocol, surveillance of drug accumulation ri
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The biochemical cell culture activities and properties of bi
2021-09-18

The biochemical, cell culture activities and properties of bicyclic carboxamides are compiled in , with the prototype of the series, 4-fluorobenzyl carboxamide , displaying an antiviral profile comparable to the spirocyclic carboxamide . The introduction of a small hydrophobic methyl () and chlori
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We have confirmed that HO suppressed TLR MyD dependent signa
2021-09-18

We have confirmed that HO-2 suppressed TLR4/MyD88-dependent signaling by down-regulating the downstream factors (TNF-α and IL-6) in mouse cerebral vascular endothelial cells [13]. In this study, HO-2 overexpression mouse model was generated and to investigated the role of HO-2 in macrophage inflamma
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br Discussion Considering cardiovascular risk factors there
2021-09-18

Discussion Considering cardiovascular risk factors, there was a significant difference in prevalence of dyslipidemia in both groups, 57.5% in HIV-infected stroke patients compared to 8.9% in the HIV-uninfected patients. These results are similar to that of Chow et al. who found a dyslipidemia pre
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Introduction Protein tyrosine phosphorylation plays key
2021-09-18

Introduction Protein-tyrosine phosphorylation plays key roles in a variety of intracellular signaling pathways involved in cell proliferation, differentiation, gene expression, cell adhesion, and metabolic changes [1]. While receptor-type tyrosine kinases localize to the plasma membrane, most of no
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The components of the SAGA complex including Gcn have recent
2021-09-18

The components of the SAGA complex including Gcn5 have recently been found to be involved in regulating pathways that are required for development and virulence in different species under the environmental stresses, around 10% of S. cerevisiae genes are activated by the transcriptional coactivator S
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br Introduction Regulation of transcription
2021-09-18

Introduction Regulation of transcription is a critical event of the embryonic development and epigenetic mechanisms such as histone modifications and DNA methylation appear important in mediating temporal changes, and differences among cells/tissues, of temporary stabilized transcriptomes (Mas e
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