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The presence of in the local environment together with the
2019-04-29
The presence of in the local environment, together with the multiple modes of Zika sglt introduction and spread, highlight the urgent need: to (i) develop an active vector surveillance and early Zika virus detection system, (ii) introduce public health awareness campaigns, and (iii) establish nati
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While the evidence linking Zika
2019-04-29
While the evidence linking Zika virus infection and GBS in adults and separately between microcephaly and other neurological conditions in the fetuses of pregnant women is strong and growing, many key research and public health questions need to be addressed through comprehensive epidemiological stu
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br Methods A questionnaire survey was conducted to
2019-04-29
Methods A questionnaire survey was conducted to collect information on the practice of CRT optimization of physicians who implant CRT devices in Japan. The collected data were focused on the method used to optimize AV and VV delays, the time required for the optimization, and the frequency of rep
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The outcome of early LELCC is reported to be better
2019-04-29
The outcome of early LELCC is reported to be better than classical intra-hepatic cholangiocarcinoma (IHCC). Chan et al reported a seven-patient case series with surgically resected stage I LELCC, which demonstrated better overall survival and disease-free survival compared to randomly selected stage
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Given that strategies to avoid ONJ are likely
2019-04-29
Given that strategies to avoid ONJ are likely to be more effective than treating the condition once it occurs, it also seems sensible to reduce bisphosphonate exposure as much as possible. This can be accomplished by using less potent agents or less intensive infusion schedules, particularly in thos
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br Results There were cases where cryotherapy
2019-04-29
Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors
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Esta limita o agu a se uma vez que
2019-04-29
Esta limitação aguça‐se uma vez que, do ponto de vista das relações de trabalho, EPI-001 mineração contemporânea configura‐se como uma atividade que exige altos investimentos de capital, mas que emprega relativamente pouca força de trabalho. Assim, o outro lado da política de desregulamentação merca
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Another complication in areas approaching local elimination
2019-04-29
Another complication in areas approaching local elimination such as Haiti is high spatiotemporal variation in transmission. Steinhardt and colleagues made every effort to match malaria exposure in cases and controls by comparing individuals experiencing fever close in time and living in the same com
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The greater relative importance of indirect
2019-04-28
The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment
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When the subject of climate change is raised people
2019-04-28
When the subject of climate change is raised, people tend to think of extreme heat events, droughts, violent storms, rising sea levels, and floods. Today, we certainly live in an era of severe weather events, which will intensify if human-driven climate change continues unabated. Such events are kno
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br Possible reasons for the divergent results for
2019-04-28
Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site
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autotaxin inhibitor br Introduction Epidemiological studies
2019-04-28
Introduction Epidemiological studies have shown that viral infections such as hepatitis C virus (HCV) and hepatitis B virus (HBV) are important factors contributing to hepatocellular carcinoma (HCC) development. Chronic HCV leads to cirrhosis in approximately 20% of patients over a 10–20 year per
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Numerous clinical trials phase II and phase III have
2019-04-28
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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br Methods br Results br
2019-04-28
Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve
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Effect of atorvastatin in modulation and protection of cardi
2019-04-28
Effect of atorvastatin in modulation and protection of cardiomyocyte ischemia and inflammatory phenomena (identified as a decline in perioperative CRP, hs-cTnT, and CPK-MB levels) [15,25–27] was not confirmed in the PROFACE trial. Because of no significant differences in the clinical preoperative or
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